Specially Appointed Professor of Structural Biology and Former Dean · Graduate School of Medical Life Science
Prof. Dr. Yoshifumi Nishimura is a world-renowned pioneer in biomolecular NMR, elucidating the three-dimensional structures of human transcription factors, DNA-binding homeodomains, and epigenetic histone modifications.
NMR Structure Analysis of Transcription Factors Epigenetic Recognition Mechanisms Chromatin Remodeling Complexes Telomere Biology
View research profile ↗
Professor of Protein Engineering and Structural Biophysics · Graduate School of Medical Life Science
Prof. Dr. Jeremy R. H. Tame investigates macromolecular allostery and symmetrical protein architectures, designing synthetic repeat proteins and catalytic enzymes for bio-industrial applications.
Allosteric Protein Regulation Artificial Protein Scaffolding X-ray Crystallography De Novo Enzyme Design
View research profile ↗
Professor of Supramolecular Biochemistry and RNA Therapeutics · Laboratory of Structural Biology
Prof. Dr. Tatsuya Niimi leads structural studies into eukaryotic spliceosomes and non-coding RNA complexes, utilizing high-resolution cryo-EM to unravel molecular targets for genetic disorders.
RNA-Protein Interactions Cryo-EM of Spliceosome Complexes Antisense Oligonucleotide Design Ribosome Assembly
View research profile ↗
Professor of Molecular Pharmacology and Drug Discovery · Department of Pharmaceutical Chemistry
Prof. Dr. Masahiko Sato designs novel bifunctional degraders and kinase inhibitors, integrating structural biophysics with medicinal chemistry to overcome multidrug-resistant malignancies.
Targeted Protein Degradation (PROTACs) Small-Molecule Kinase Inhibitors Molecular Dynamics Docking Cancer Chemotherapy Resistance
View research profile ↗